Hemodynamics, fluids & transfusion
Reduction of red blood cell transfusion with a patient blood management protocol in urological and visceral surgery: a before-after study
Main findingResult — go to the resultRelative risk 0.58 95% CI 0.38–0.87Authors' conclusion
The implementation of a PBM protocol over a two-year period was associated with a reduction of transfusion in major urological and visceral surgery.
Study context
- Population
- Patients undergoing major urological and visceral surgery in a tertiary care centre
- Participants
- 488 vs 499
- Exposure
- Three-pillar Patient Blood Management (PBM) protocol vs before implementation
- 2019n = 488reference
- 2022n = 499
- Outcome
- Incidence of RBC transfusion intraoperatively or within 7 days after surgery
- Follow-up
- Within 7 days after surgery
Methodological detailshistorical vs prospective cohort, single tertiary care centre
- Historical vs prospective cohort
- Single tertiary care centre
Main finding
As reported in the abstract
Relative risk
0.58
95% CI 0.38–0.87
P = 0.01
By group
2022 vs 2019
RR 0.58 (95% CI 0.38–0.87); P = 0.01
Observational data: associations, not effects.
Further findings
Screening for iron deficiency
P < 0.01
TXA administration
P < 0.01
Haemoglobin <100 g.L-1 at discharge
P = 0.41
Haemoglobin concentration before transfusion
P = 0.02
Safety
Medical complications
- Comparable between the groups
Original publication
Reduction of red blood cell transfusion with a patient blood management protocol in urological and visceral surgery: a before-after study. Anaesth Crit Care Pain Med. Published 23 May 2024. doi:10. 1016/ j. accpm. 2024. 101395
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