Hemodynamics, fluids & transfusion

Reduction of red blood cell transfusion with a patient blood management protocol in urological and visceral surgery: a before-after study

Anaesth Crit Care Pain MedPublished Before-after study

Main findingResult — go to the resultRelative risk 0.58 95% CI 0.38–0.87

Authors' conclusion

The implementation of a PBM protocol over a two-year period was associated with a reduction of transfusion in major urological and visceral surgery.

Study context

Population
Patients undergoing major urological and visceral surgery in a tertiary care centre
Participants
488 vs 499
Exposure
Three-pillar Patient Blood Management (PBM) protocol vs before implementation
  • 2019n = 488reference
  • 2022n = 499
Outcome
Incidence of RBC transfusion intraoperatively or within 7 days after surgery
Follow-up
Within 7 days after surgery
Methodological detailshistorical vs prospective cohort, single tertiary care centre
  • Historical vs prospective cohort
  • Single tertiary care centre

Main finding

As reported in the abstract

Relative risk

0.58

95% CI 0.38–0.87

P = 0.01

By group

2022 vs 2019
RR 0.58 (95% CI 0.38–0.87); P = 0.01

Observational data: associations, not effects.

Further findings

Screening for iron deficiency

P < 0.01

TXA administration

P < 0.01

Haemoglobin <100 g.L-1 at discharge

P = 0.41

Haemoglobin concentration before transfusion

P = 0.02

Safety

Medical complications

Comparable between the groups

Original publication

Reduction of red blood cell transfusion with a patient blood management protocol in urological and visceral surgery: a before-after study. Anaesth Crit Care Pain Med. Published 23 May 2024. doi:10.1016/j.accpm.2024.101395

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