Cardiothoracic & vascular anesthesia
Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction of iron deficiency and anemia on red blood cell transfusion
An erratum to this article was published (J Clin Anesth, Jan 2025 ↗)
Authors' conclusion
This study suggests that health care education and systematic deficiency correction are associated with reduced RBC transfusion rates in elective CPB surgery.
Study context
- Population
- Patients undergoing elective cardiopulmonary bypass (CPB) surgery, Clinique Pasteur, Toulouse, France343 per group after matching
- Participants
- 343 / 343 / 343
- Comparison
- Two-step patient blood management (PBM) program vs pre-PBM retrospective cohort
- pre-PBMn = 343reference
- PBMen = 343
- PBMcn = 343
- Primary endpoint
- Proportion of patients requiring RBC transfusions during hospital stay
Methodological detailsnon-randomized, two-step protocol, propensity-score matched, single-centre
- Non-randomized
- Two-step protocol
- Propensity-score matched
- Single-centre
Primary result
As reported in the abstract
Each group vs pre-PBMAdjusted odds ratio (95% CI)
PBMe
0.59(0.44–0.79)
PBMc
0.44(0.32–0.60)
- Significant reduction in overall red blood cell (RBC) transfusion rate
- 40.6%
Secondary outcomes
Transfusions >2 units, total RBC units, allogeneic blood products, total bleeding volume on Day 1
- Reduced with PBM
Mortality and hospital LOS
- No significant differences
Original publication
Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction of iron deficiency and anemia on red blood cell transfusion. J Clin Anesth. Published 14 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →