Relationship between preinduction electroencephalogram patterns and propofol sensitivity in adult patients
Authors' conclusion
Preinduction EEG, particularly relative delta power, is associated with propofol requirements during the induction of general anesthesia.
Study context
- Population
- Healthy adults undergoing total intravenous anesthesia (TIVA) with propofol
- Participants
- 70 adults
- Outcome
- Relationship between preinduction EEG and propofol requirement (effect-site target concentration) for loss of responsiveness
Main finding
As reported in the abstract
Correlation of preinduction EEG with propofol requirement
- Higher relative delta power: greater propofol requirement (ρ = 0.47)
- p < 0.01
- Higher absolute delta power: greater propofol requirement (ρ = 0.34)
- p = 0.01
- Higher relative beta power: less propofol required (ρ = −0.33)
- p < 0.01
Observational data: associations, not effects.
Original publication
Relationship between preinduction electroencephalogram patterns and propofol sensitivity in adult patients. J Clin Monit Comput. Published 2 April 2024. doi:10.
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