Remimazolam for sedation: A protocol for a systematic review with meta‐analysis, trial sequential analysis, and GRADE approach
Study context
- Population
- Adults requiring sedation for a diagnostic or therapeutic procedure, or due to other circumstances
- Planned comparison
- Remimazolam vs placebo or other sedatives
- Primary endpoint
- Sedation success rate, respiratory complications, and hemodynamic complications
Methodological detailstrial sequential analysis, GRADE approach, PRISMA, Risk of bias assessed with Risk of Bias 2 Tool; random error with trial sequential analysis; certainty of evidence with GRADE
- Trial sequential analysis
- GRADE approach
- PRISMA
- Risk of bias assessed with Risk of Bias 2 Tool; random error with trial sequential analysis; certainty of evidence with GRADE
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Remimazolam for sedation: A protocol for a systematic review with meta‐analysis, trial sequential analysis, and GRADE approach. Acta Anaesthesiol Scand. Published 14 August 2023. doi:10. 1111/ aas. 14316
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