Hemodynamics, fluids & transfusion
Risk Stratification in Predicting Cardiogenic Shock 30-Day Mortality admitted to Intensive Care Units (ICU): beyond the Prognostic Performance of Shock Academic Research Consortium (SHARC) and Society for Cardiovascular Angiography and Interventions (SCAI) Classifications
Authors' conclusion
SHARC etiological classification provides complementary discrimination for 30-day mortality compared with SCAI staging alone, suggesting that shock pathophysiology influences patient outcomes.
Study context
- Population
- Consecutive adults admitted to ICU with cardiogenic shock
- Participants
- 1,366 adults · 2 centres
- Exposure
- SHARC etiological classes (AMI-CS, HF-CS, secondary-CS, post-cardiotomy-CS); prognostic value of SHARC vs SCAI classification
- AMI-CSn = 303
- HF-CSn = 56
- secondary-CSn = 433
- post-cardiotomy-CSn = 574
- Outcome
- All-cause mortality
- Follow-up
- 30 days
Methodological detailsbicentric, consecutive adults
- Bicentric
- Consecutive adults
Main finding
As reported in the abstract
30-day mortality by SHARC class
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | SHARC | SCAI | Combined SHARC, SCAI and hemodynamic model |
|---|---|---|---|
| Incremental prognostic value added to clinical variables | |||
| ΔAIC | −48.3 | −20.0 | — not stated in the abstract |
| AUC | 0.734 | 0.723 | 0.819 |
| R2 | 0.198 | 0.172 | 0.355 |
— not stated in the abstract
Independent predictors of mortality (multivariable analysis)
- Age, epinephrine use, vasopressin use, arterial lactate, right ventricular dysfunction and SHARC classification independent predictors (all P < 0.05)
Incremental prognostic value added to clinical variables
- Combined model demonstrated the best performance
Original publication
Risk Stratification in Predicting Cardiogenic Shock 30-Day Mortality admitted to ICU: beyond the Prognostic Performance of SHARC and SCAI Classifications. Ann Intensive Care. Published 20 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →