Organ support & nutrition

Should Obesity Be an Exclusion Criterion for Extracorporeal Membrane Oxygenation Support? A Scoping Review

Anesth AnalgPublished Scoping review

Authors' conclusion

Although the included studies are limited to retrospective analyses and display a heterogeneity in definitions of obesity and comparison groups, the currently available literature suggests that outcomes and complications of ECMO therapy are equivalent in obese patients as compared to nonobese patients.

Study context

Population
Patients requiring extracorporeal membrane oxygenation (ECMO) support (VV-ECMO in non-COVID-19 acute respiratory distress syndrome (ARDS), VV-ECMO in COVID-19 ARDS, VA-ECMO for all indications, combined venoarterial (VA)- and VV-ECMO); literature January 2003 to March 202326 publications
Comparison
Obese vs nonobese patients supported with ECMO
Outcome
Outcomes and complications of ECMO therapy in obese patients
Methodological detailslibrarian-assisted search, 4 databases (PubMed, Web of Science, Embase, Cochrane Library), two independent reviewers
  • Librarian-assisted search
  • 4 databases (PubMed, Web of Science, Embase, Cochrane Library)
  • Two independent reviewers

Main finding

As reported in the abstract

Outcomes and complications of ECMO therapy
  • Outcomes and complications of ECMO equivalent in obese vs nonobese patients
  • Included studies limited to retrospective analyses
  • Heterogeneity in definitions of obesity and comparison groups

Further findings

Included publications by ECMO type

VV-ECMO in non-COVID-19 ARDS
7
ECMO in COVID-19 ARDS
6
VA-ECMO
8
Combined VA- and VV-ECMO
5
  • 354 publications screened on titles and abstracts; 30 full-text reviewed

Original publication

Should Obesity Be an Exclusion Criterion for Extracorporeal Membrane Oxygenation Support? A Scoping Review. Anesth Analg. Published 27 November 2023. doi:10.1213/ane.0000000000006745

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