Should Obesity Be an Exclusion Criterion for Extracorporeal Membrane Oxygenation Support? A Scoping Review
Authors' conclusion
Although the included studies are limited to retrospective analyses and display a heterogeneity in definitions of obesity and comparison groups, the currently available literature suggests that outcomes and complications of ECMO therapy are equivalent in obese patients as compared to nonobese patients.
Study context
- Population
- Patients requiring extracorporeal membrane oxygenation (ECMO) support (VV-ECMO in non-COVID-19 acute respiratory distress syndrome (ARDS), VV-ECMO in COVID-19 ARDS, VA-ECMO for all indications, combined venoarterial (VA)- and VV-ECMO); literature January 2003 to March 202326 publications
- Comparison
- Obese vs nonobese patients supported with ECMO
- Outcome
- Outcomes and complications of ECMO therapy in obese patients
Methodological detailslibrarian-assisted search, 4 databases (PubMed, Web of Science, Embase, Cochrane Library), two independent reviewers
- Librarian-assisted search
- 4 databases (PubMed, Web of Science, Embase, Cochrane Library)
- Two independent reviewers
Main finding
As reported in the abstract
Outcomes and complications of ECMO therapy
- Outcomes and complications of ECMO equivalent in obese vs nonobese patients
- Included studies limited to retrospective analyses
- Heterogeneity in definitions of obesity and comparison groups
Further findings
Included publications by ECMO type
- VV-ECMO in non-COVID-19 ARDS
- 7
- ECMO in COVID-19 ARDS
- 6
- VA-ECMO
- 8
- Combined VA- and VV-ECMO
- 5
- 354 publications screened on titles and abstracts; 30 full-text reviewed
Original publication
Should Obesity Be an Exclusion Criterion for Extracorporeal Membrane Oxygenation Support? A Scoping Review. Anesth Analg. Published 27 November 2023. doi:10. 1213/ ane. 0000000000006745
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