Respiratory failure & ventilation
Society of Critical Care Medicine Guidelines for the Administration of Neuromuscular Blockade in Adults With Acute Respiratory Distress Syndrome
Methodological detailsGRADE methodology, systematic review for each question, 21-member multidisciplinary panel
- GRADE methodology
- Systematic review for each question
- 21-member multidisciplinary panel
Recommendations
As issued by the authors
- conditional
Use neuromuscular blocking agents (NMBAs) in adults with acute respiratory distress syndrome (ARDS) with Pao2/Fio2 less than 150
Equipoise (no recommendation for or against) on titratable vs fixed-dose NMBA dosing, a monitoring-based strategy for assessing depth of sedation and analgesia before or during neuromuscular blockade, and NMBAs for patients who are proned, due to overall lack of evidence and patient safety and experience concerns
Original publication
Society of Critical Care Medicine Guidelines for the Administration of Neuromuscular Blockade in Adults With Acute Respiratory Distress Syndrome. Crit Care Med. Published 3 March 2026. doi:10.
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