Respiratory failure & ventilation
Subphenotypes in Acute Respiratory Distress Syndrome: Universal Steps Toward Treatable Traits
Study context
- Population
- Patients with acute respiratory distress syndrome (ARDS)
- Outcome
- ARDS subphenotypes identified in the literature
Methodological details6-step roadmap framework, 6-step roadmap: reproducible subphenotypes, parsimonious bedside classification, possible interventions, prospective validation of classification, subphenotype-targeted randomized clinical trial (RCT), implementation in guidelines and clinical practice
- 6-step roadmap framework
- 6-step roadmap: reproducible subphenotypes, parsimonious bedside classification, possible interventions, prospective validation of classification, subphenotype-targeted RCT, implementation in guidelines and clinical practice
Main finding
As reported in the abstract
- Respiratory physiology, lung morphology and systemic inflammatory biology subphenotypes identified
- Lung morphology and systemic inflammatory biology subphenotypes currently being tested prospectively in RCTs
Original publication
Subphenotypes in Acute Respiratory Distress Syndrome: Universal Steps Toward Treatable Traits. Anesth Analg. Published 19 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →