Cardiothoracic & vascular anesthesia

Temporal Trends and Severity of Postoperative Delirium in Cardiac Surgery: Insights from a Systematic Review and Meta-analysis

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis

Study context

Population
Adults undergoing cardiac surgery assessed for delirium with validated tools, 2009 to March 2024
Participants
5,126 adults · 27 studies
Outcome
Incidence of POD
Methodological detailsPRISMA, random-effects meta-analysis, subgroup analyses, meta-regression
  • PRISMA
  • Random-effects meta-analysis
  • Subgroup analyses
  • Meta-regression

Pooled result

As reported in the abstract

Overall incidence of POD

Overall postoperative delirium (POD) incidence

25.1%

95% CI 21.8%–28.3%

Further pooled results

Duration of POD

Mean duration, days
2.378 (95% CI 2.086-2.671)

Time to onset of POD

Onset, days
1.706 (95% CI 1.198-2.214)

Severity of POD (maximum Confusion Assessment Method score, scale 0 to 19)

Maximum score
9.308 (95% CI 7.309-11.307)
  • Only 3 studies

Subgroup analyses (heterogeneity)

No significant differences in outcomes

Original publication

Temporal Trends and Severity of Postoperative Delirium in Cardiac Surgery: Insights from a Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 17 May 2025. doi:10.1053/j.jvca.2025.05.020

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