Cardiothoracic & vascular anesthesia

The association of right ventricular function with outcomes after cardiac surgery: a systematic review

Can J AnaesthPublished Systematic review of observational studies

Authors' conclusion

Pre- and perioperative assessment of RV function using at least two quantitative echocardiographic parameters may offer prognostic information in patients undergoing cardiac surgery.

Study context

Population
Adults (≥ 18 yr) undergoing cardiac surgery with an echocardiogram within six months of surgery, intraoperatively, or shortly after surgery27 observational studies
Outcome
Postoperative mortality
Follow-up
Up to five years
Methodological detailsfocused systematic review, PubMed and MEDLINE searched, 1 January 1990 to 22 April 2024; 7,187 potentially relevant studies identified
  • Focused systematic review
  • PubMed and MEDLINE searched, 1 January 1990 to 22 April 2024; 7,187 potentially relevant studies identified

Pooled result

As reported in the abstract

  • Right ventricular fractional area change (RVFAC) (most commonly reported) inconsistently associated with mortality
  • Tricuspid annular plane systolic excursion (TAPSE) and strain consistently associated with mortality

Further pooled results

RVFAC inconsistently associated with major adverse cardiac events (MACE)
Right ventricular (RV) myocardial performance index (MPI) the most consistent predictor of MACE across studies

Original publication

The association of right ventricular function with outcomes after cardiac surgery: a systematic review. Can J Anaesth. Published 12 February 2025. doi:10.1007/s12630-024-02898-9

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