Respiratory failure & ventilation

The effects of hypnosis and music intervention on comfort and anxiety during weaning from mechanical ventilation: A pilot study

J Crit CarePublished Prospective interventional trial

Authors' conclusion

In this pilot study, a single session of either hypnosis or music intervention was demonstrated to effectively reduce anxiety and enhance comfort, in critically ill patients facing extended or challenging MV weaning.

Study context

Population
Critically ill patients with extended or challenging weaning from mechanical ventilation (MV)75 eligible
Participants
29 patients
Exposure
Hypnosis vs music intervention
  • Hypnosisn = 15
  • Music interventionn = 14
Outcome
Patient comfort and anxiety levels (Visual Analog Scale (VAS))
Methodological detailssingle-centre, pilot
  • Single-centre
  • Pilot

Main finding

As reported in the abstract

Comfort and anxiety (VAS), before to after intervention
Hypnosis: comfort increased from 4 [2-6] to 8 [7-9]
p < 0.01
Music intervention: comfort increased from 5 [4-6] to 7 [5-8]
p < 0.01
Hypnosis: anxiety decreased from 5 [5-7] to 3 [2-5]
p < 0.01
Music intervention: anxiety decreased from 6 [5-8] to 4 [3-6]
p < 0.01

Observational data: associations, not effects.

Further findings

Respiratory rate

Hypnosis: decreased from 28 [25-37] to 24 [23-35]
P < 0.01
Music intervention: unchanged

Heart rate

Significant decline from baseline after both interventions, then reverted to initial values

MAP (mmHg)

Hypnosis: elevation from 94 (86-110) to 99 (80-108) mmHg
P = 0.01
Music intervention: reduction from 87 (75-101) to 82 (74-88) mmHg
P = 0.01

Cortisol (μg/L)

Music intervention: decreased from 249 [175-291] to 207 [145-242] μg/L
P = 0.02
Hypnosis: unchanged
  • Both p = 0.04

EEG power

Both interventions: significant decrease in slow delta power and increase in theta and alpha power, indicative of a hypnosis-like state

Original publication

The effects of hypnosis and music intervention on comfort and anxiety during weaning from mechanical ventilation: A pilot study. J Crit Care. Published 3 March 2025. doi:10.1016/j.jcrc.2025.155044

Composed by AI from the published abstract and checked against it. How Briefs are made →

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