Hemodynamics, fluids & transfusion
The haemodynamic effects of pneumoperitoneum on pulse pressure variation – a prospective, observational study
Authors' conclusion
PPV derived from a generalised additive model increased approximately 50% from the induction of pneumoperitoneum to an IAP of 12 mmHg.
Study context
- Population
- Patients undergoing oesophagectomyincluded in final analysis
- Participants
- 34 patients
- Exposure
- Before vs after induction of pneumoperitoneum
- Outcome
- PPV derived from a generalised additive model (PPVGAM) with induction of pneumoperitoneum and increase in IAP
Main finding
As reported in the abstract
PPVGAM
PPVGAM increase factor, intra-abdominal pressure (IAP) baseline to 12 mmHg
1.49
95% CI 1.25–1.77
Observational data: associations, not effects.
Further findings
Stroke volume variation (SVV) (HemoSphere monitor)
- Increase factor
- 1.25 (95% CI 1.13-1.39, p < 0.001)
PPV (HemoSphere monitor)
- Increase factor
- 1.14 (95% CI 1.00-1.29, p = 0.048)
Original publication
The haemodynamic effects of pneumoperitoneum on pulse pressure variation – a prospective, observational study. J Clin Monit Comput. Published 5 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →