Hemodynamics, fluids & transfusion
The hypotension prediction index versus mean arterial pressure in predicting intraoperative hypotension: A clinical perspective
Main finding · Time-to-event difference, HPI-85 popup vs MAP-70Result — go to the resultgain 0.58 min 95% CI 0.57–0.58Authors' conclusion
Using HPI-85 popup alerts does not provide additional prediction time over MAP-alerts in the 70 to 75 mmHg range, but they may be preferred due to higher PPV values.
Study context
- Population
- Adults scheduled for elective non-cardiac surgery lasting over two hours, academic hospital in the Netherlands, 2018–202091 analysed
- Participants
- 105 adults
- Exposure
- Hypotension prediction index (HPI) popup alerts vs mean arterial pressure (MAP)-alerts in predicting intraoperative hypotension
- Outcome
- Time-to-hypotensive event intervals predicted by HPI popup alerts and MAP-alerts
Methodological detailssingle-centre
- Single-centre
Main finding
Time-to-event difference, HPI-85 popup vs MAP-70
gain
0.58 min
95% CI 0.57–0.58
As reported in the abstract
Observational data: associations, not effects.
Further findings
- PPV — HPI-85 popup
- 55.6 (95% CI 55.4–55.8) %
- PPV: MAP-75 20.5 (95% CI 20.3–20.6) %
Missed hypotensive events
- Similar: between one to three percent
Instant HPI-85 vs MAP-72 alerts
- Comparable performance, both suboptimal PPV around 30%
MAP-alerts with 40-s time-dependence
- Differences across the three metrics levelled, aligning closely with HPI-85 popup alerts
Original publication
The hypotension prediction index versus mean arterial pressure in predicting intraoperative hypotension: A clinical perspective. Eur J Anaesthesiol. Published 27 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →