Cardiothoracic & vascular anesthesia
The impact of frailty on functional recovery after cardiac surgery—a case control study
Authors' conclusion
Short- and medium-term measures of good functional recovery were lower in 'frail' patients, and longer-term survival was also significantly reduced.
Study context
- Population
- Patients undergoing cardiac surgeryincluded in final analysis
- Participants
- 669 patients
- Comparison
- Frail vs non-frail patients
- Frailn = 224
- Outcome
- Functional recovery: DAOH30 and DAH365
Methodological detailsmoderation analysis
- Moderation analysis
Main finding
As reported in the abstract
DAOH30 and DAH365
- Frail patients spent fewer days at home in the first 30 days, largely due to days requiring advanced cardiovascular support
- Frail patients spent fewer days at home in the first year, most days lost to patients who died in the first year
Further findings
- Frailty prevalence — Frail
- 33.5%
ICU stay, level 3 support, hospital LOS
- Frail patients had longer ICU stay, required level 3 cardiovascular and respiratory support for longer and had longer hospital LOS
Moderation by deprivation (Welsh Index of Multiple Deprivation (WIMD))
- Interaction term not significant for DAOH30 or DAH365; no evidence of moderation
Frailty prevalence
- Frail more likely to have COPD, HF and DM and be in lowest deprivation decile; frailty not associated with sex or advanced age
Original publication
The impact of frailty on functional recovery after cardiac surgery—a case control study. Perioper Med (Lond). Published 23 April 2025. doi:10. 1186/ s13741-025-00526-8
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