Cardiothoracic & vascular anesthesia

The impact of frailty on functional recovery after cardiac surgery—a case control study

Perioper Med (Lond)Published Case control study

Authors' conclusion

Short- and medium-term measures of good functional recovery were lower in 'frail' patients, and longer-term survival was also significantly reduced.

Study context

Population
Patients undergoing cardiac surgeryincluded in final analysis
Participants
669 patients
Comparison
Frail vs non-frail patients
  • Frailn = 224
Outcome
Functional recovery: DAOH30 and DAH365
Methodological detailsmoderation analysis
  • Moderation analysis

Main finding

As reported in the abstract

DAOH30 and DAH365
  • Frail patients spent fewer days at home in the first 30 days, largely due to days requiring advanced cardiovascular support
  • Frail patients spent fewer days at home in the first year, most days lost to patients who died in the first year

Further findings

Frailty prevalence — Frail
33.5%

ICU stay, level 3 support, hospital LOS

Frail patients had longer ICU stay, required level 3 cardiovascular and respiratory support for longer and had longer hospital LOS

Moderation by deprivation (Welsh Index of Multiple Deprivation (WIMD))

Interaction term not significant for DAOH30 or DAH365; no evidence of moderation

Frailty prevalence

Frail more likely to have COPD, HF and DM and be in lowest deprivation decile; frailty not associated with sex or advanced age

Original publication

The impact of frailty on functional recovery after cardiac surgery—a case control study. Perioper Med (Lond). Published 23 April 2025. doi:10.1186/s13741-025-00526-8

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