Cardiothoracic & vascular anesthesia
The Impact of Perioperative Hemodynamic and Blood Pressure Variability in Outcomes and Mortality: A Comprehensive Systematic Review
Authors' conclusion
Perioperative BPV appears to be a crucial factor influencing postoperative outcomes in cardiac surgery patients.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 16,407 patients · 15 studies
- Comparison
- Higher vs lower perioperative blood pressure (BP) variability
- Outcome
- Association of perioperative BPV with mortality and cardiovascular/clinical outcomes
Pooled result
As reported in the abstract
Mortality and clinical outcomes
30-day mortality, patients with fewer comorbidities and perioperative risk
0.2% to 0.5%
30-day mortality, higher-risk patients
42.4% to 60.7%
p < 0.001
Higher risk of acute kidney injury (AKI) per unit increase in BP SD
23.2%
Increased incidence of postoperative delirium
15%
Original publication
The Impact of Perioperative Hemodynamic and Blood Pressure Variability in Outcomes and Mortality: A Comprehensive Systematic Review. J Cardiothorac Vasc Anesth. Published 18 August 2025. doi:10.
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