Cardiothoracic & vascular anesthesia
The Long-Term Impact of Diastolic Dysfunction After Routine Cardiac Surgery
Authors' conclusion
These findings suggested that DD may be associated with poor short-term and long-term outcomes.
Study context
- Population
- Patients undergoing isolated coronary, isolated valvular, or concomitant coronary and valvular surgery with TTE within 6 months before surgerymedian follow-up 4.0 years
- Participants
- 8,682 patients
- Exposure
- Grade I, II or III diastolic dysfunction vs no diastolic dysfunction (DD) on preoperative TTE
- No DDn = 4,375reference
- Grade I DDn = 3,034
- Grade II DDn = 1,066
- Grade III DDn = 207
- Outcome
- Operative mortality
Methodological detailssingle-centre, consecutive cardiac surgeries 2010–2021, Median (IQR) time of TTE before surgery 6 (2-29) days
- Single-centre
- Consecutive cardiac surgeries 2010–2021
- Median (IQR) time of TTE before surgery 6 (2-29) days
Main finding
As reported in the abstract
P = 0.001
Observational data: associations, not effects.
Further findings
Long-term survival (Kaplan-Meier) · median follow-up 4.0 (IQR: 1.7-6.5) years
- Kaplan-Meier survival estimates lower in the grade III DD group than in the rest of the cohort
Safety
Postoperative complications: AF, prolonged mechanical ventilation (>24 hours), AKI, any RBC transfusion, reexploration for bleeding, LOS
- Higher in the grade III DD group vs the rest of the cohort
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Long-Term Impact of Diastolic Dysfunction After Routine Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 6 February 2023. doi:10.
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