Respiratory failure & ventilation
Time course of electrical activity of the diaphragm (EAdi) in the peri extubation period and its role as predictor of extubation failure in difficult to wean patients
Authors' conclusion
In difficult-to-wean patients, EAdi increases significantly between the phases before the SBT, the SBT and post-extubation period and is significantly higher in patients experiencing extubation failure.
Study context
- Population
- Difficult-to-wean patients undergoing invasive mechanical ventilationanalysed
- Participants
- 31 patients
- Exposure
- Extubation failure vs success
- Extubation failuren = 6
- Outcome
- EAdi time course and prediction of extubation failure
Main finding
As reported in the abstract
- EAdi increased significantly from before spontaneous breathing trials (SBT) to SBT and post-extubation, up to 24 h
- p < 0.001
- EAdi > 30 μV during SBT: sensitivity for extubation failure
- 92%
- EAdi > 30 μV during SBT: specificity for extubation failure
- 67%
Observational data: associations, not effects.
Original publication
Time course of electrical activity of the diaphragm (EAdi) in the peri extubation period and its role as predictor of extubation failure in difficult to wean patients. Crit Care. Published 17 September 2024. doi:10.
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