Tracheal intubating conditions in elderly patients when train-of-four count is zero after rocuronium 0.6 or 0.9 mg/kg. A secondary analysis
Primary resultResult — go to the resultDifference 28 % 95% CI 3–53Authors' conclusion
The proportion of patients with vocal cords in abducted position was significantly larger after rocuronium 0.9 mg/kg compared to rocuronium 0.6 mg/kg at TOF 0 monitored at the ulnar nerve.
Study context
- Population
- Elderly surgical patients; NMB monitored by acceleromyography with train-of-four (TOF) stimulation at the ulnar nerve
- Participants
- 52 patients
- Comparison
- Rocuronium 0.9 vs 0.6 mg/kg
- Rocuronium 0.6 mg/kgn = 36reference
- Rocuronium 0.9 mg/kgn = 16
- Primary endpoint
- Proportion of patients with vocal cords in abducted position at TOF 0
Primary result
As reported in the abstract
Difference
28 %
95% CI 3–53
P = 0.05
By group
Rocuronium 0.9 mg/kg vs Rocuronium 0.6 mg/kg
difference 28 % (95% CI 3–53); P = 0.05
Secondary outcomes
| Outcome | Rocuronium 0.9 mg/kg | Difference (%) (95% CI) | P value | |
|---|---|---|---|---|
| Excellent intubating conditions (Fuchs-Buder scale) | 62.5% | 32.5 (4–61) | P = 0.03 | |
| −50050100Difference, % (linear scale) |
Intubating Difficulty Score (IDS)
- No significant difference in IDS
Onset time of rocuronium
- No significant difference in onset time
- difference 19 s 19 s (95% CI −5-43)
Duration of action of rocuronium
- Duration of action significantly longer in the 0.9 mg/kg group
- difference 29 min 29 min (95% CI 10-47)
Original publication
Tracheal intubating conditions in elderly patients when train-of-four count is zero after rocuronium 0.6 or 0.9 mg/kg. A secondary analysis. J Clin Monit Comput. Published 29 April 2023. doi:10.
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