Cardiothoracic & vascular anesthesia
Transversus Thoracic Muscle Plane Block For Postoperative Pain in Pediatric Cardiac Surgery: A Systematic Review And Meta-Analysis of Randomized And Observational Studies
Pooled result · Modified objective pain scoreResult — go to the resultWMD −2.20 95% CI −2.73 to −1.68Authors' conclusion
Very low- to low-certainty evidence showed that TTMPB in pediatric patients undergoing cardiac surgery may reduce postoperative pain, opioid consumption, ICU length of stay, and extubation time.
Study context
- Population
- Pediatric patients 2 months to 12 years undergoing cardiac surgery
- Participants
- 601 patients · 6 studies
- Comparison
- Transversus thoracic muscle plane block (TTMPB) vs no block or sham block
- Outcome
- Modified objective pain score
- Follow-up
- 12 hours
Methodological detailsGRADE certainty assessment, randomized trials and retrospective studies
- GRADE certainty assessment
- Randomized trials and retrospective studies
Pooled result
As reported in the abstract
WMD
−2.20
95% CI −2.73 to −1.68
TTMPB vs No block/sham block
WMD −2.20 (95% CI −2.73 to −1.68)
Further pooled results
| Outcome | WMD (95% CI) | |
|---|---|---|
| Modified objective pain score · 24 hours | −1.76 (−2.09 to −1.42) | |
| −3−2−101Difference (linear scale) |
| Outcome | WMD (μg/kg) (95% CI) | |
|---|---|---|
| Intraoperative opioid consumption | −3.83 (−5.90 to −1.76) | |
| Postoperative opioid consumption | −2.51 (−2.84 to −2.18) | |
| −10−505Difference, μg/kg (linear scale) |
| Outcome | WMD (hours) (95% CI) | |
|---|---|---|
| ICU LOS | −5.56 (−8.30 to −2.83) | |
| Extubation time | −2.13 (−4.21 to −0.05) | |
| −10−505Difference, hours (linear scale) |
Retrospective studies
- Results consistent with RCTs (very low certainty)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Transversus Thoracic Muscle Plane Block For Postoperative Pain in Pediatric Cardiac Surgery: A Systematic Review And Meta-Analysis of Randomized And Observational Studies. J Cardiothorac Vasc Anesth. Published 23 February 2024. doi:10.
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