Respiratory failure & ventilation
Ventilator-associated events in adults: A secondary analysis assessing the impact of monitoring ventilator settings on outcomes
Authors' conclusion
The modification of ventilator settings (consistent with ventilator-associated events) was associated with worse outcomes among adults with prolonged mechanical ventilation.
Study context
- Population
- Adults on mechanical ventilation2,706 ventilator-days
- Participants
- 261 adults
- Comparison
- Ventilator-associated events (VAE) tier vs modified tiers with shorter follow-up (VAE24), lower oxygenation requirements (light-VAE) or both (light VAE24)
Primary result
As reported in the abstract
VAE incidence (per 1,000 ventilator-days)
Further findings
Intensive care unit (ICU) mortality with a VAE tier
- Trend to increase in ICU mortality with a VAE tier
- from 32% to 44%
Duration of mechanical ventilation (MV), ICU LOS and hospital LOS with a VAE tier
- Extra days of ventilation (21 vs. 8)
- 13
- Extra ICU days (23 vs. 12)
- 11
- Extra hospitalization days (31 vs. 14)
- 7
- VAE tier outperformed the modified tiers
Cohort duration of MV and ICU LOS
- Duration of MV, median (IQR), days
- 9 (5-21)
- ICU LOS, median (IQR), days
- 14 (8-26)
Original publication
Ventilator-associated events in adults: A secondary analysis assessing the impact of monitoring ventilator settings on outcomes. Anaesth Crit Care Pain Med. Published 1 March 2024. doi:10.
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