Cardiothoracic & vascular anesthesia
Volatile Anesthetic Use Versus Total Intravenous Anesthesia for Patients Undergoing Heart Valve Surgery: A Nationwide Population-Based Study
Main findingResult — go to the resultHazard ratio 0.98 95% CI 0.90–1.07Authors' conclusion
Compared with TIVA, volatile anesthetic use was not associated with reduced postoperative mortality risk in patients undergoing heart valve surgery.
Study context
- Population
- Adults undergoing heart valve surgery in Korea, 2010–2019
- Participants
- 30,755 adults
- Exposure
- Volatile anaesthetics vs total intravenous anesthesia (TIVA)
- Outcome
- Cumulative 1-year all-cause mortality
- Follow-up
- 1 year
Methodological detailsstabilized inverse probability of treatment weighting, health insurance claim database
- Stabilized inverse probability of treatment weighting
- Health insurance claim database
Main finding
As reported in the abstract
Hazard ratio
0.98
95% CI 0.90–1.07
P = 0.602
Volatile anesthetics vs TIVA
HR 0.98 (95% CI 0.90–1.07); P = 0.602
- Overall incidence of 1-year mortality
- 8.5%
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Cumulative long-term (beyond 1 year) mortality · median (IQR) follow-up 4.8 (2.6-7.6) yearsAfter stabilized IPTW | 0.98 (0.93–1.04) | P = 0.579 | |
| 0.512Hazard ratio (log scale) |
Original publication
Volatile Anesthetic Use Versus Total Intravenous Anesthesia for Patients Undergoing Heart Valve Surgery: A Nationwide Population-Based Study. Anesth Analg. Published 21 November 2023. doi:10.
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