Cardiothoracic & vascular anesthesia
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Authors' conclusion
Using volatile sedation is associated with few minutes additional workload in assembling and enables a significantly accelerated evaluation of vulnerable patient groups.
Study context
- Population
- Patients after open cardiac valve surgery, tertiary university hospital
- Comparison
- Volatile vs propofol sedation
- Primary endpoint
- Time to extubation
Methodological detailsprospective, single-centre
- Prospective
- Single-centre
Primary result
As reported in the abstract
P < 0.001
Further findings
Time to eye-opening · significantly earlier with volatile sedation
P < 0.001
Time to command compliance · significantly earlier with volatile sedation
P < 0.001
- Workload (set-up time) of volatile sedation
- 9:56 · median · ± 4:16 min · min
Workload (set-up time) of volatile sedation
- Significantly increased workload with volatile sedation
CPB time
- CPB time did not differ between the groups
- 101 (IQR 81; 113) versus 112 (IQR 79; 136) minutes
- p = 0.36
Safety
- No differences in complications
Original publication
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial. Crit Care. Published 5 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →