Cardiothoracic & vascular anesthesia
Avoidance of Hyperoxemia Versus Routine Hyperoxia During Cardiopulmonary Bypass in Children With Cyanotic Congenital Heart Disease—A Systematic Review and Meta‐Analysis
Pooled resultResult — go to the resultSMD −0.25 95% CI −0.52-0.03Authors' conclusion
No significant differences in postoperative outcomes were observed between oxygenation strategies aimed at avoiding hyperoxemia and routine hyperoxic management during CPB.
Study context
- Population
- Children with cyanotic congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass (CPB)7 studies (6 RCTs, 1 observational)
- Comparison
- Avoidance of hyperoxemia vs routine hyperoxia during CPB
- Outcome
- Postoperative intubation time
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
SMD
−0.25
95% CI −0.52-0.03
P = 0.077
Avoidance of hyperoxemia vs Routine hyperoxia
SMD −0.25 (95% CI −0.52-0.03); P = 0.077
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Avoidance of Hyperoxemia Versus Routine Hyperoxia During Cardiopulmonary Bypass in Children With Cyanotic Congenital Heart Disease—A Systematic Review and Meta‐Analysis. Paediatr Anaesth. Published 25 March 2026. doi:10.
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