Cardiothoracic & vascular anesthesia
Central and Mixed Venous Oxygen Saturation in Cardiac Surgery: A Systematic Review and Meta-analysis
Pooled result · MortalityResult — go to the resultRelative risk 5.23 95% CI 2.82–9.69Authors' conclusion
Low ScvO2 or SvO2 identified patients at higher risk after cardiac surgery.
Study context
- Population
- Adult or pediatric cardiac surgery patients
- Participants
- 38,217 participants · 29 studies
- Comparison
- Low or supranormal vs normal ScvO2 or SvO2
- Outcome
- Mortality across ScvO2 or SvO2 strata
Methodological detailsmostly observational studies, Risk of bias generally low to moderate, confounding the main concern
- Mostly observational studies
- Risk of bias generally low to moderate, confounding the main concern
Pooled result
Mortality
Relative risk
5.23
95% CI 2.82–9.69
P < 0.00001
Low vs Normal
RR 5.23 (95% CI 2.82–9.69); P < 0.00001
As reported in the abstract
Original publication
Central and Mixed Venous Oxygen Saturation in Cardiac Surgery: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 5 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →