Cardiothoracic & vascular anesthesia
Central/mixed venous oxygen saturation and lactate levels might be of limited use as physiologic transfusion triggers in cardiac surgery: Results of a retrospective analysis
Authors' conclusion
Hb, SvO 2 and lactate levels were only weakly correlated with each other, and changes in SvO 2 and lactate levels in response to pRBC transfusion did not correlate with pretransfusion Hb.
Study context
- Population
- Adult (≥18 years) cardiac surgery patients in a 22-bed intensive care unit (ICU), tertiary academic centre, Austria20,542 blood gas analyses
- Participants
- 5,025 participants
- Primary endpoint
- Pearson r and r2 between Hb, mixed/central venous oxygen saturation (SvO2) and lactate; and between ΔSvO2, Δlactate and pretransfusion Hb
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Correlation haemoglobin (Hb) vs SvO2 (r2), statistically significant but weak; P < 0.001
0.026
No correlation ΔSvO2 vs pretransfusion Hb (r2); P = 0.13
0.002
No correlation Δlactate vs pretransfusion Hb (r2); P = 0.087
0.003
Original publication
Central/mixed venous oxygen saturation and lactate levels might be of limited use as physiologic transfusion triggers in cardiac surgery: Results of a retrospective analysis. Eur J Anaesthesiol. Published 27 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →