Cardiothoracic & vascular anesthesia
Mixed Venous Oxygen Saturation Has a Poor Association with Cardiac Index during Early Intensive Care Unit Stay after Cardiac Surgery
Authors' conclusion
Factors affecting oxygen consumption and demand weaken the association between SvO2 and CI values in the early ICU recovery phase after cardiac surgery.
Study context
- Population
- Adult cardiac surgical patients, tertiary university hospital, 2007 to 2020, with pulmonary artery catheter (PAC) measurements in the early intensive care unit (ICU) staypaired CI and SvO2 values
- Participants
- 4,958 patients
- Outcome
- CI change per 10% change of SvO2 (entire cohort)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
CI change per 10% SvO2 change at ICU admission
0.36 L/min/m²
95% CI 0.34–0.38
CI change per 10% SvO2 change at 4 hours (0.31-0.36)
0.33 L/min/m²
Observational data: associations, not effects.
Further findings
SvO2 and CI values
- SvO2 at ICU admission, median (IQR 63-72%)
- 68%
- SvO2 4 hours later, median (IQR 61-71%)
- 66%
- CI at ICU admission (2.03-2.79)
- 2.34 L/min/m²
- CI 4 hours later (2.15-2.86)
- 2.48 L/min/m²
Association between CI and SvO2 (SvO2 less than 60%) (subgroup)
- Association between CI and SvO2 weakened further
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mixed Venous Oxygen Saturation Has a Poor Association with Cardiac Index during Early Intensive Care Unit Stay after Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 22 April 2025. doi:10.
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