Cardiothoracic & vascular anesthesia
Clinical Outcomes in Patients with Phosphate Abnormalities After Cardiac Surgery: A Retrospective Cohort Study
Main finding · Time to tracheal extubationResult — go to the resultIncident rate ratio 1.26 95% CI 10%–44%Authors' conclusion
Hyperphosphatemia in the immediate postoperative period after cardiac surgery is associated with adverse clinical outcomes.
Study context
- Population
- Patients undergoing nontransplant cardiac surgery with CPB, August 2009 to December 2020
- Participants
- 2,659 patients
- Exposure
- Hyperphosphatemic vs Normal phosphate
- Hypophosphatemicn = 502
- Normal phosphaten = 1,905reference
- Hyperphosphatemicn = 252
- Outcome
- Time to tracheal extubation
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incident rate ratio
1.26
95% CI 10%–44%
P = 0.001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| In-hospital mortalityHyperphosphatemic vs Normal phosphate | 4.0 (2.3–7.1) | P < 0.001 | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | Acceleration factor (95% CI) | P value |
|---|---|---|
| Hospital LOSHyperphosphatemic vs Normal phosphate · 37% longer | 0.63 (−43% to −30%) | P < 0.001 |
Hospital LOS
- Association not found for hypophosphatemia
In-hospital mortality
- Association not found for hypophosphatemia
Original publication
Clinical Outcomes in Patients with Phosphate Abnormalities After Cardiac Surgery: A Retrospective Cohort Study. Anesth Analg. Published 9 October 2024. doi:10. 1213/ ane. 0000000000007229
Composed by AI from the published abstract and checked against it. How Briefs are made →