Cardiothoracic & vascular anesthesia
The Association Between Hypophosphatemia and Lactic Acidosis After Cardiac Surgery With Cardiopulmonary Bypass: A Retrospective Cohort Study
Authors' conclusion
Hypophosphatemia is associated with lactic acidosis in the immediate postoperative period in cardiac surgery patients.
Study context
- Population
- Patients undergoing nontransplant cardiac surgery with CPB, single academic centre, August 2009 to December 2020
- Participants
- 681 vs 2,579
- Exposure
- Low phosphate vs normal phosphate at intensive care unit (ICU) admission
- Low phosphaten = 681
- Normal phosphaten = 2,579reference
- Outcome
- Severe lactic acidosis
- Follow-up
- ICU admission
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Low phosphate vs Normal phosphateEstimate (95% CI)
Unadjusted logistic regression
OR 1.9(1.5–2.3)
Adjusted for several possible confounders
aOR 1.4(1.1–1.7)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Association Between Hypophosphatemia and Lactic Acidosis After Cardiac Surgery With Cardiopulmonary Bypass: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 25 November 2022. doi:10. 1053/ j. jvca. 2022. 11. 032
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