Cardiothoracic & vascular anesthesia
Comparing Echocardiography and Right Heart Catheterization for Mortality Prediction in Pulmonary Hypertension
Authors' conclusion
In critically ill patients with PH, mortality was best associated with systemic arterial pressure and integrated hemodynamic relationships (pulmonary-to-systemic ratios and SPP).
Study context
- Population
- Adults with pulmonary hypertension (PH) admitted to a cardiac care unit who underwent right heart catheterization (RHC) with a recorded TTE within 2 months
- Participants
- 159 adults
- Outcome
- Mortality
- Follow-up
- 12 months
Methodological detailssingle-centre, tertiary care university hospital cardiac ICU
- Single-centre
- Tertiary care university hospital cardiac ICU
Main finding
As reported in the abstract
12-month mortality and its RHC/TTE predictors
- Mortality rate
- 21% (34 of 159)
- Univariate: pulmonary artery systolic pressure/SBP ratio ≥ 0.50, OR
- 3.47, p = 0.01
- Univariate: Mean pulmonary artery pressure (mPAP)/mean arterial pressure (MAP) ratio ≥ 0.44, OR
- 3.89, p = 0.01
- Univariate: Pulmonary vascular resistance (PVR)/systemic vascular resistance (SVR) ≥ 0.12, OR
- 3.03, p = 0.002
- Univariate: MAP ≥ 84.3 mmHg (lower mortality), OR
- 0.96, p = 0.003
- Univariate: Systemic perfusion pressure (SPP) (MAP - RAP) ≥ 75.2 mmHg (lower mortality), OR
- 0.96, p = 0.002
- Multivariate: MAP, OR
- 0.96, p = 0.004
- Multivariate: mPAP/MAP, OR
- 10.12, p = 0.02
- Multivariate: PVR/SVR, OR
- 15.79, p = 0.001
- Multivariate: SPP, OR
- 0.96, p = 0.002
Observational data: associations, not effects.
Further findings
TTE predictors
- Qualitative right ventricle size and function (100% available) not predictive; TTE reporting otherwise incomplete
Original publication
Comparing Echocardiography and Right Heart Catheterization for Mortality Prediction in Pulmonary Hypertension. J Cardiothorac Vasc Anesth. Published 7 March 2026. doi:10. 1053/ j. jvca. 2026. 03. 012
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