Cardiothoracic & vascular anesthesia
Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial
Study context
- Population
- Adults (≥18 years) scheduled for elective valvular and/or coronary surgery with cardiopulmonary bypass (CPB), San Pedro University Hospital, Logroño, Spainplanned
- Participants
- 90 adults
- Planned comparison
- IV lidocaine vs saline placebo
- Primary endpoint
- Interleukin 6 level
- Follow-up
- 6 hours postoperatively
Methodological detailssingle-centre, parallel-group, double-blind, placebo-controlled, intention-to-treat, Analysis on an ITT basis
- Single-centre
- Parallel-group
- Double-blind
- Placebo-controlled
- Intention-to-treat
- Analysis on an ITT basis
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial. J Cardiothorac Vasc Anesth. Published 10 January 2026. doi:10.
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