Cardiothoracic & vascular anesthesia

Frequency of blood lactate elevation following esophagectomy and its association to postoperative complications

Acta Anaesthesiol ScandPublished Retrospective cohort study

Authors' conclusion

In conclusion, elevated blood lactate in the immediate time following esophagectomy showed a weak association to intensive care and length of stay but not anastomotic leak.

Study context

Population
Patients undergoing esophagectomy at Karolinska University Hospital 2016–2018 (most minimally invasive, n = 130)130 minimally invasive
Participants
153 patients
Outcome
Hospital LOS
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Hospital LOS and its association with blood lactate

Median hospital LOS (days)

14

Observational data: associations, not effects.

Secondary outcomes

Postoperative hyperlactatemia (peak lactate, first night) · first night following operation

Peak lactate >1.6 mmol/L
93%
Peak lactate >3.5 mmol/L
27%

Anastomotic leak

No statistical differences in lactate between those with and without anastomotic leak at any time point

Factors related to elevated lactate in first 12-16 h · first 12-16 h postoperatively

Related to surgical factors (open technique, surgery time, perioperative bleeding), not to patient factors (ASA-class, Charlson comorbidity index, sex, age) or cumulative fluid balance

Original publication

Frequency of blood lactate elevation following esophagectomy and its association to postoperative complications. Acta Anaesthesiol Scand. Published 30 December 2022. doi:10.1111/aas.14181

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