Cardiothoracic & vascular anesthesia
Frequency of blood lactate elevation following esophagectomy and its association to postoperative complications
Authors' conclusion
In conclusion, elevated blood lactate in the immediate time following esophagectomy showed a weak association to intensive care and length of stay but not anastomotic leak.
Study context
- Population
- Patients undergoing esophagectomy at Karolinska University Hospital 2016–2018 (most minimally invasive, n = 130)130 minimally invasive
- Participants
- 153 patients
- Outcome
- Hospital LOS
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Hospital LOS and its association with blood lactate
Median hospital LOS (days)
14
Observational data: associations, not effects.
Secondary outcomes
Postoperative hyperlactatemia (peak lactate, first night) · first night following operation
- Peak lactate >1.6 mmol/L
- 93%
- Peak lactate >3.5 mmol/L
- 27%
Anastomotic leak
- No statistical differences in lactate between those with and without anastomotic leak at any time point
Factors related to elevated lactate in first 12-16 h · first 12-16 h postoperatively
- Related to surgical factors (open technique, surgery time, perioperative bleeding), not to patient factors (ASA-class, Charlson comorbidity index, sex, age) or cumulative fluid balance
Original publication
Frequency of blood lactate elevation following esophagectomy and its association to postoperative complications. Acta Anaesthesiol Scand. Published 30 December 2022. doi:10. 1111/ aas. 14181
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