Cardiothoracic & vascular anesthesia

Hemodynamic Safety and Effect of Dexmedetomidine on Superficial Cervical Block Quality for Carotid Endarterectomy: A Prospective Study

J Cardiothorac Vasc AnesthPublished Randomised controlled trial

Authors' conclusion

The addition of 50 μg of dexmedetomidine to 0.5% levobupivacaine and 2% lidocaine for SCB did not influence the hemodynamics and frequency of adverse effects. The median sensory block duration time showed no statistical difference between the groups, but the quality of analgesia postoperatively was much improved in the study group.

Study context

Population
ASA II–III patients undergoing elective carotid endarterectomy (CEA) under ultrasound-guided superficial cervical block (SCB), university hospital
Participants
60 patients
Comparison
Intervention vs Control
  • Interventionn = 30
  • Controln = 30reference
Methodological detailsprospective, double-blinded, single-centre
  • Prospective
  • Double-blinded
  • Single-centre

Primary result

As reported in the abstract

Onset and duration of sensory block and analgesia
  • Time to first analgesia longer in the intervention group than control
  • No difference in duration of sensory block between groups
  • Log-rank test: significant difference in probability of NRS <3

Safety

Minimum effects on hemodynamic parameters
No differences in incidence of adverse effects

Original publication

Hemodynamic Safety and Effect of Dexmedetomidine on Superficial Cervical Block Quality for Carotid Endarterectomy: A Prospective Study. J Cardiothorac Vasc Anesth. Published 10 June 2023. doi:10.1053/j.jvca.2023.06.009

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