Cardiothoracic & vascular anesthesia
High‐dose glucocorticoids in the treatment of postoperative pain after video‐assisted thoracoscopic surgery—protocol for systematic review and meta‐analysis
Study context
- Population
- Adults undergoing video-assisted thoracoscopic surgery (VATS)
- Planned comparison
- Higher-dose glucocorticoids vs lower doses, placebo or no treatment
- Primary endpoint
- Standardised dynamic pain scores
- Follow-up
- Within 24 h
Methodological detailsCochrane methodology, PRISMA, GRADE, trial sequential analysis, sensitivity and subgroup analyses, Secondary outcomes: opioid use, time to first mobilisation, hospital LOS, NRS >3 within first 24 h, Exploratory outcomes: opioid- and glucocorticoid-related adverse effects (major and minor)
- Cochrane methodology
- PRISMA
- GRADE
- Trial sequential analysis
- Sensitivity and subgroup analyses
- Secondary outcomes: opioid use, time to first mobilisation, hospital LOS, NRS >3 within first 24 h
- Exploratory outcomes: opioid- and glucocorticoid-related adverse effects (major and minor)
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
High‐dose glucocorticoids in the treatment of postoperative pain after video‐assisted thoracoscopic surgery—protocol for systematic review and meta‐analysis. Acta Anaesthesiol Scand. Published 23 January 2025. doi:10.
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