Cardiothoracic & vascular anesthesia
Intraoperative Oxygenation and Microcirculatory Changes Following Off-pump Coronary Artery Bypass Grafting: An Exploratory Secondary Analysis of a Randomized Clinical Trial
Authors' conclusion
Patients receiving 80% oxygen during OPCAB had significantly better postoperative microcirculatory profiles than those receiving 30% oxygen.
Study context
- Population
- Adults undergoing off-pump coronary artery bypass grafting (OPCAB), 3 teaching hospitalssublingual microscopy 52 vs 51
- Comparison
- 80% vs 30% intraoperative oxygen
Methodological detailsgeneralized estimating equations
- Generalized estimating equations
Primary result
As reported in the abstract
Microcirculatory parameters
- All microcirculatory parameters similar between groups
Further findings
De Backer score, all vessels · end of surgery
P = 0.011
De Backer score, small vessels · end of surgery
P = 0.024
Recovery score
P = 0.001
| Outcome | 30% oxygen | 80% oxygen | P value |
|---|---|---|---|
| Thenar muscle tissue oxygenation immediately before vascular occlusion | 74.0% (SD 9.3) | 78.4% (SD 10.5) | P = 0.031 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Intraoperative Oxygenation and Microcirculatory Changes Following Off-pump Coronary Artery Bypass Grafting: An Exploratory Secondary Analysis of a Randomized Clinical Trial. J Cardiothorac Vasc Anesth. Published 6 February 2025. doi:10.
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