Cardiothoracic & vascular anesthesia
Nonanemic Iron Deficiency in Cardiac Surgery: A Retrospective Observational Study
Authors' conclusion
NAID is common and can lead to progression to anemia and increased transfusion.
Study context
- Population
- Adults preassessed and undergoing cardiac surgery at a single tertiary referral center
- Participants
- 537 adults
- Exposure
- Groups by hemoglobin and ferritin: Nonanemic iron deficiency (NAID), nonanemic iron replete, iron-deficiency anemia (IDA), non-iron-deficiency anemia
- NAIDn = 179
- Outcome
- Incidence of NAID
Methodological detailssingle-centre, tertiary referral center
- Single-centre
- Tertiary referral center
Main finding
As reported in the abstract
NAID
33.3%
179
Observational data: associations, not effects.
Secondary outcomes
| Outcome | NAID | Nonanemic iron replete | P value |
|---|---|---|---|
| Became anemic while awaiting surgeryNAID vs Nonanemic iron replete | 9.5% | 3.3% | P = 0.02 |
| Allogeneic transfusionNAID vs Nonanemic iron replete | 33% | 23% | P = 0.04 |
| Hemoglobin at follow-upNAID vs Nonanemic iron replete · poorer recovery of hemoglobin in NAID | 13.2 ± 1.46 g/dL | 13.9 ± 1.46 g/dL | P < 0.001 |
Original publication
Nonanemic Iron Deficiency in Cardiac Surgery: A Retrospective Observational Study. J Cardiothorac Vasc Anesth. Published 31 May 2024. doi:10.
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