Cardiothoracic & vascular anesthesia
Preoperative anemia and anemia treatment in cardiac surgery: a systematic review and meta-analysis
Pooled result · MortalityResult — go to the resultOdds ratio 2.5 95% CI 2.2–2.9Authors' conclusion
Preoperative anemia is associated with mortality and morbidity after cardiac surgery.
Study context
- Population
- Patients undergoing cardiac surgery
- Participants
- 159,025 patients · 35 studies
- Comparison
- Preoperative anemia vs No anemia
- Outcome
- Mortality
Methodological detailsrandom-effects meta-analysis, meta-regression, trial sequential analysis, GRADE certainty of evidence
- Random-effects meta-analysis
- Meta-regression
- Trial sequential analysis
- GRADE certainty of evidence
Pooled result
As reported in the abstract
Odds ratio
2.5
95% CI 2.2–2.9
P < 0.001
Preoperative anemia vs No anemia
OR 2.5 (95% CI 2.2–2.9); P < 0.001
Further pooled results
Mortality with short-term preoperative anemia treatment (secondary analysis, 7 studies, 1,012 patients)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Short-term preoperative anemia treatment | 1.1 (0.65–1.9) | P = 0.69 | |
| 0.512Odds ratio (log scale) |
Mortality risk by Hb level and sex proportion (meta-regression)
- Lower Hb levels and lower proportions of male patients associated with increased mortality risk
Length of stay (LOS) and postsurgical complications
- Preoperative anemia associated with increased LOS and postsurgical complications
Mortality with short-term preoperative anemia treatment (secondary analysis, 7 studies, 1,012 patients)
- Trial sequential analysis: insufficient evidence to conclude benefit or harm of treatment programs
Original publication
Preoperative anemia and anemia treatment in cardiac surgery: a systematic review and meta-analysis. Can J Anaesth. Published 6 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →