Cardiothoracic & vascular anesthesia
Pulmonary artery wave reflection and right ventricular function after lung resection
Authors' conclusion
Pulsatile afterload increased after lung resection. The unilateral increase in operative pulmonary artery wave reflection resulted in redistribution of blood flow through the nonoperative pulmonary artery and was associated with right ventricular dysfunction.
Study context
- Population
- Patients scheduled for open lobectomy for suspected lung cancer
- Participants
- 27 patients
- Exposure
- Preoperative vs postoperative day 2 vs 2 months after open lobectomy
- Outcome
- Operative pulmonary artery wave reflection index
Methodological detailscardiovascular magnetic resonance imaging (MRI)
- Cardiovascular MRI
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
RV ejection fraction vs operative PA wave reflection and flow redistribution · Postoperative Day 2
- Impaired RV ejection fraction associated with increased operative PA wave reflection (P=0.028)
- r=−0.480
- Impaired RV ejection fraction associated with PA blood flow redistribution (P=0.011)
- r=−0.545
RV ejection fraction and RV strain vs PA blood flow redistribution · 2 months
- Impaired RV ejection fraction associated with PA blood flow redistribution (P=0.002)
- r=−0.634
- Impaired RV strain associated with PA blood flow redistribution (P=0.017)
- r=0.540
Original publication
Pulmonary artery wave reflection and right ventricular function after lung resection. Br J Anaesth. Published 15 September 2022. doi:10.
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