Cardiothoracic & vascular anesthesia
The Impact of Blood Pressure Below Personalized Lower Cerebral Autoregulation Limit on Outcomes After Cardiac Surgery: A Retrospective Study
Authors' conclusion
These findings indicate that LLA-related metrics have limited utility for predicting MMOM.
Study context
- Population
- Patients undergoing cardiovascular surgery at a university hospital
- Participants
- 686 cardiovascular surgeries
- Exposure
- Exposure: area under the time-pressure curve for mean arterial pressure (MAP) below the lower limit of autoregulation (LLA)
- Outcome
- Major morbidity and mortality (MMOM: stroke, AKI, low cardiac output syndrome, mechanical ventilation >48 hours, postoperative mortality)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Association of AUCABP<LLA with MMOM
- No significant association between AUCABP<LLA and major morbidity and mortality (MMOM)
- p > 0.05
Observational data: associations, not effects.
Further findings
MMOM components: operative mortality and low cardiac output syndrome
- Operative mortality associated with AUCABP<LLA
- P < 0.05
- Low cardiac output syndrome associated with AUCABP<LLA
- P < 0.05
- Controlling for preoperative hemoglobin levels and logistic EuroSCORE
Original publication
The Impact of Blood Pressure Below Personalized Lower Cerebral Autoregulation Limit on Outcomes After Cardiac Surgery: A Retrospective Study. J Cardiothorac Vasc Anesth. Published 15 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →