Cardiothoracic & vascular anesthesia
Tissue Oxygen Saturation Combined With Serum Lactic Acid Can Predict Cardiac Surgery–Associated Acute Kidney Injury
Authors' conclusion
Tissue oxygen saturation measured during CPB and elevated postoperative serum lactate levels are valuable early parameters for predicting CSA-AKI risk in patients undergoing cardiac surgery with CPB.
Study context
- Population
- Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB)
- Participants
- 391 patients
- Outcome
- Predictors of CSA-AKI
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- SctO2 cutoff during CPB
- 56.75%
- Saturation (StO2) cutoff during CPB
- 65.85%
- SctO2 cutoff after CPB
- 60.15%
- StO2 cutoff after CPB
- 67.20%
- Combined model of 5 independent variables, AUC
- 91.8% (95% CI 0.762-0.887)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Tissue Oxygen Saturation Combined With Serum Lactic Acid Can Predict Cardiac Surgery–Associated Acute Kidney Injury. J Cardiothorac Vasc Anesth. Published 18 August 2025. doi:10.
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