Cardiothoracic & vascular anesthesia
Use of rocuronium and sugammadex for video-assisted thoracoscopic surgery is associated with reduced duration of chest tube drainage: a propensity score-matched analysis
Authors' conclusion
During general anaesthesia for VATS, compared with cisatracurium and neostigmine, use of rocuronium and sugammadex was associated with a significant decrease in the incidence of postoperative delayed removal of the chest tube, atelectasis, and pulmonary consolidation.
Study context
- Population
- Patients undergoing video-assisted thoracoscopic surgery (VATS) after tracheal intubation under GA, with quantitative neuromuscular monitoring and one 24 Fr chest tube140 per group matched
- Participants
- 151 vs 547
- Exposure
- Rocuronium and sugammadex vs cisatracurium and neostigmine
- Rocuronium and sugammadexn = 151
- Cisatracurium and neostigminen = 547reference
- Outcome
- Duration of chest tube drainage after surgery
Methodological detailssingle-centre, propensity-score matched
- Single-centre
- Propensity-score matched
Main finding
As reported in the abstract
P = 0.049
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Delayed chest tube removal63% reduction | 0.37 (0.20–0.67) | P = 0.005 | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | P value |
|---|---|
| Postoperative atelectasisLower incidence | P = 0.047 |
| Postoperative consolidationLower incidence | P = 0.008 |
Delayed chest tube removal per 1 h increase in duration of anaesthesia
- 1.57-fold increase
- 1.57 (95% CI 1.25-1.96; P=0.005)
Original publication
Use of rocuronium and sugammadex for video-assisted thoracoscopic surgery is associated with reduced duration of chest tube drainage: a propensity score-matched analysis. Br J Anaesth. Published 26 August 2022. doi:10. 1016/ j. bja. 2022. 07. 046
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