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Critical Care
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Identification of a robust metabolic signature associated with hospital-acquired pneumonia and response to interferon-gamma treatment in critically ill patients
Randomized controlled trialSepsis & infection
Crit Care
Major haemorrhage and blood product utilisation in patients receiving VA ECMO for cardiogenic shock: a multicentre observational study (OBLEX)
Cohort studyOrgan support & nutrition
Crit Care
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End-inspiratory pause enhances ventilation efficiency without increasing autoPEEP in patients with COPD during controlled ventilation
Randomized controlled trialRespiratory failure
Crit Care
Augmenting the Simplified Acute Physiology Score II for intensive care unit mortality prediction and benchmarking: a French nationwide study
Cohort studyICU sedation & recovery
Crit Care
Pediatric Intensive Care Core Outcomes–a modified Delphi consensus process (PIC-CO)
Guideline or statementPediatric
Crit Care
Awake burr hole craniotomy for chronic subdural hematoma: a phase 2 randomized controlled trial
Randomized controlled trialNeuro
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Adverse events as key risk factors for in-hospital mortality in intensive care units
Cross-sectional studySafety & education
Crit Care
Well-being and sense of security of intubated patients in intensive care units: a patient co-constructed dedicated scale
Diagnostic or prognostic studySafety & education
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Deep white matter MRI predicts outcomes in coma of various etiologies: a cohort study
Diagnostic or prognostic studyNeuro
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Early trajectories of pulmonary hemodynamics in ARDS patients undergoing V-V ECMO: key determinants and prognostic impact
Cohort studyOrgan support & nutrition
Crit Care
Evaluation of days alive out of hospital as an outcome after intensive care admission: a national retrospective cohort study
Cohort studyICU sedation & recovery
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Crit Care
Monotherapy versus combination therapy in severe Legionella pneumonia: a multicenter retrospective observational study
Cohort studySepsis & infection
Crit Care
Diaphragm neurostimulation mitigates the adverse cardiopulmonary effects of positive pressure ventilation
Randomized controlled trialRespiratory failure
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Association between initial norepinephrine dose and minute by minute mean arterial pressure
Cohort studyHemodynamics & fluids
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Blood N1-methyladenosine (m1A) RNA modification and outcome after cardiac arrest
Diagnostic or prognostic studyCardiac arrest
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The effect of plasma versus crystalloids on intravascular volume, tissue perfusion and tissue oxygenation: a randomized controlled trial in a human endotoxemia model
Randomized controlled trialHemodynamics & fluids
Crit Care
Detecting the metabolic transition to personalize nutritional timing: model development and preliminary validation in a large ICU cohort
Cohort studyOrgan support & nutrition
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On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial
Secondary analysisCardiac arrest