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Intensive Care Medicine
Latest from Intensive Care Medicine
Intensive Care Med
Identification and validation of robust hospital-acquired pneumonia subphenotypes associated with all-cause mortality: a multi-cohort derivation and validation
Diagnostic or prognostic studySepsis & infection
Intensive Care Med
Intensive Care Med
Outcomes in immunocompromised patients with acute hypoxemic respiratory failure treated by high-flow nasal oxygen
Cohort studyRespiratory failure
Intensive Care Med
Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial
Randomized controlled trialSepsis & infection
Intensive Care Med
Intensive Care Med
Intensive Care Med
Intensive Care Med
Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome
Secondary analysisSepsis & infection
Intensive Care Med
A consensus of European experts on the definition of ventilator-associated pneumonia recurrences obtained by the Delphi method: the RECUVAP study
Guideline or statementSepsis & infection
Intensive Care Med
Sepsis subphenotypes, theragnostics and personalized sepsis care
Research articleSepsis & infection
Intensive Care Med
A common longitudinal intensive care unit data format (CLIF) for critical illness research
Cohort studyICU sedation & recovery
Intensive Care Med
Management of high-risk acute pulmonary embolism: an emulated target trial analysis
Cohort studyOrgan support & nutrition
Intensive Care Med
Discussing expected long-term quality of life in the ICU: effect on experiences and outcomes of patients, family, and clinicians—a randomized clinical trial
Randomized controlled trialICU sedation & recovery
Intensive Care Med
Intensive Care Med
Persistent severe acute kidney injury is a major modifiable determinant of outcome during critical illness
Cohort studyOrgan support & nutrition
Intensive Care Med
INHALE WP3, a multicentre, open-label, pragmatic randomised controlled trial assessing the impact of rapid, ICU-based, syndromic PCR, versus standard-of-care on antibiotic stewardship and clinical outcomes in hospital-acquired and ventilator-associated pneumonia
Randomized controlled trialSepsis & infection
Intensive Care Med
Intensive Care Med
ESICM consensus-based recommendations for the management of very old patients in intensive care
Guideline or statementSafety & education
Intensive Care Med
Invasive fungal infections in patients with liver disease: immunological and clinical considerations for the intensive care unit
Research articleSepsis & infection
Intensive Care Med
Intensive Care Med
Serum chloride concentration and outcomes in adults receiving intravenous fluid therapy with a balanced crystalloid solution or 0.9% sodium chloride
Secondary analysisHemodynamics & fluids
Intensive Care Med
Intensive Care Med
Role of major cardiovascular surgery-induced metabolic reprogramming in acute kidney injury in critical care
Cohort studyCardiothoracic & vascular
Intensive Care Med
A multivariable prediction model for invasive pulmonary aspergillosis in immunocompromised patients with acute respiratory failure (IPA-GRRR-OH score)
Diagnostic or prognostic studyRespiratory failure
Intensive Care Med
Intensive Care Med
The association between pain, analgesia, and delirium among critically ill adults: a systematic review and meta-analysis
Meta-analysisICU sedation & recovery
Intensive Care Med
Best clinical model predicting extubation failure: a diagnostic accuracy post hoc analysis
Diagnostic or prognostic studyRespiratory failure
Intensive Care Med
Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial
Secondary analysisSepsis & infection
Intensive Care Med
Intensive Care Med
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock
Cohort studySepsis & infection
Intensive Care Med
What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients
Research articleSepsis & infection
Intensive Care Med
Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study
Cohort studyOrgan support & nutrition
Intensive Care Med
Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method
Guideline or statementSepsis & infection
Intensive Care Med
Rethinking ARDS classification: oxygenation impairment fails to predict VILI risk
Cohort studyRespiratory failure
Intensive Care Med
Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults
Guideline or statementOrgan support & nutrition
Intensive Care Med
Early physiologic changes after awake prone positioning predict clinical outcomes in patients with acute hypoxemic respiratory failure
Secondary analysisRespiratory failure
Intensive Care Med
Chlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial
Randomized controlled trialCardiothoracic & vascular
Intensive Care Med
Intensive Care Med
Intensive Care Med
Spontaneous breathing trials should be adapted for each patient according to the critical illness. A new individualised approach: the GLOBAL WEAN study
Randomized controlled trialRespiratory failure