Critical Care

1. Crit Care19 Jun 2025

   Association of epinephrine and outcome in cardiac arrest with refractory shockable rhythm: a population-based, propensity-score matched analysis

   Cohort studyCardiac arrest

2. Crit Care17 Jun 2025

   Optimizing microbiological surveillance during selective digestive decontamination in the intensive care unit: an in silico simulation study

   Research articleSepsis & infection

3. Crit Care17 Jun 2025

   Sedation and analgesia in post-cardiac arrest care: a post hoc analysis of the TTM2 trial

   Secondary analysisCardiac arrest

4. Crit Care13 Jun 2025

   Real-time changes in pulse pressure during a 10-second end-expiratory occlusion test reliably detect preload responsiveness

   Diagnostic or prognostic studyHemodynamics & fluids

5. Crit Care13 Jun 2025

   From indication to initiation of invasive intracranial pressure monitoring time differences between neurosurgeons and intensive care physicians: can intracranial hypertension dose be reduced? TIMING-ICP, a multicenter, observational, prospective study

   Cohort studyNeuro

6. Crit Care12 Jun 2025

   Invasive group A streptococcus infections in the intensive care unit: an unsupervised cluster analysis of a multicentric retrospective cohort

   Cohort studySepsis & infection

7. Crit Care6 Jun 2025

   A large language model improves clinicians’ diagnostic performance in complex critical illness cases

   Cohort studySafety & education

8. Crit Care6 Jun 2025

   Tumour necrosis factor-alpha inhibitors decrease mortality in COVID-19: a systematic review and meta-analysis

   Meta-analysisSafety & education

9. Crit Care5 Jun 2025

   The metabolic and autoregulatory profile of reversible delayed cerebral ischemia in unconscious patients after aneurysmal subarachnoid hemorrhage: a prospective multimodal neuromonitoring cohort study

   Cohort studyNeuro

10. Crit Care5 Jun 2025

    Volatile sedation in critically ill adults undergoing mechanical ventilation: a meta-analysis of randomized controlled trials

    Meta-analysisICU sedation & recovery

11. Crit Care4 Jun 2025

    Performance of broad-spectrum targeted next-generation sequencing in lower respiratory tract infections in ICU patients: a prospective observational study

    Cohort studySepsis & infection

12. Crit Care3 Jun 2025

    Impact of the Japanese clinical practice guidelines for management of sepsis and septic shock (J-SSCG) 2020 on real-world adherence and interhospital variation: a nationwide inpatient database study

    Cohort studySepsis & infection

13. Crit Care3 Jun 2025

    Prevalence, risk factors and consequences of early clinical deterioration under non-invasive ventilation in emergency department patients: a prospective, multicentre, observational study of the French IRU Network

    Cohort studyRespiratory failure

14. Crit Care3 Jun 2025

    Diagnostic performance of the recruitment-to-inflation ratio to assess lung recruitability by PEEP in ARDS. a computed tomography study

    Diagnostic or prognostic studyRespiratory failure

15. Crit Care3 Jun 2025

    Exploring the association between computed tomography (CT)-derived skeletal muscle mass and short- and long-term mortality in critically ill patients: a systematic review and meta-analysis

    Meta-analysisICU sedation & recovery

16. Crit Care2 Jun 2025

    The value of dynamic cerebral compliance monitoring after pediatric traumatic brain injury: a STARSHIP study sub-analysis

    Secondary analysisNeuro

17. Crit Care2 Jun 2025

    Accuracy of the modified Global Burden of Disease International Classification of Diseases coding methods for identifying sepsis: a prospective multicentre cohort study

    Diagnostic or prognostic studySepsis & infection

18. Crit Care27 May 2025

    Trajectories of fluid management after the initiation of renal replacement therapy in critically ill patients: a secondary analysis of the STARRT-AKI trial

    Secondary analysisOrgan support & nutrition

19. Crit Care26 May 2025

    Spontaneous diuresis in combination with furosemide stress test (SD-FST) as predictor for successful liberation from kidney replacement therapy: a prospective observational study

    Cohort studyOrgan support & nutrition

20. Crit Care26 May 2025

    Novel biomarkers for predicting successful liberation of renal replacement therapy for acute kidney injury: a systematic review

    Meta-analysisOrgan support & nutrition

21. Crit Care26 May 2025

    ORAKLE: Optimal Risk prediction for mAke30 in patients with sepsis associated AKI using deep LEarning

    Cohort studyOrgan support & nutrition

22. Crit Care23 May 2025

    Computed tomography perfusion assessment of poor neurological outcome in comatose cardiac arrest patients (CANCCAP): a prospective study

    Cohort studyCardiac arrest

23. Crit Care22 May 2025

    First dose target attainment with extended infusion regimens of piperacillin and meropenem

    Cohort studySepsis & infection

24. Crit Care21 May 2025

    Cerebral perfusion pressure targets after traumatic brain injury: a reappraisal

    Cohort studyNeuro

25. Crit Care20 May 2025

    Biomarkers in acute kidney injury settings to predict interventions and outcomes: the MARKISIO study

    Randomized controlled trialOrgan support & nutrition

26. Crit Care19 May 2025

    Labour market attachment before and after hospitalisation for sepsis: a Danish cohort study

    Cohort studySepsis & infection

27. Crit Care19 May 2025

    Severe listeriosis in intensive care units: insights from a retrospective multicentric study

    Cohort studySepsis & infection

28. Crit Care19 May 2025

    Reliability of pre-admission patient-reported outcome measures postoperatively assessed via proxies: a prospective, multicenter observational study

    Cohort studyPerioperative

29. Crit Care19 May 2025

    Identifying a unique signature of sepsis in patients with pre-existing cirrhosis

    Cohort studySepsis & infection

30. Crit Care19 May 2025

    Plasma H3.1 nucleosomes as biomarkers of infection, inflammation and organ failure

    Cohort studySepsis & infection

31. Crit Care16 May 2025

    Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review

    Research articleHemodynamics & fluids

32. Crit Care16 May 2025

    Optimum electrical impedance tomography-based PEEP and recruitment-to-inflation ratio in patients with severe ARDS on venovenous ECMO

    Mechanistic studyRespiratory failure

33. Crit Care16 May 2025

    The “mechanical paradox” unveiled: a physiological study

    Mechanistic studyRespiratory failure

34. Crit Care15 May 2025

    Traditional Chinese medicine for sepsis: advancing from evidence to innovative drug discovery

    Research articleSepsis & infection

35. Crit Care13 May 2025

    Peri-intubation complications in critically ill obese patients: a secondary analysis of the international INTUBE cohort

    Secondary analysisAirway

36. Crit Care13 May 2025

    Diaphragmatic ultrasound and its relationship to breathing effort and load: a prospective observational study

    Cohort studyRespiratory failure

37. Crit Care12 May 2025

    The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis

    Meta-analysisOrgan support & nutrition

38. Crit Care12 May 2025

    Effect of early adjunctive vasopressin initiation for septic shock patients: a target trial emulation

    Cohort studySepsis & infection

39. Crit Care9 May 2025

    Time to administer polymyxin B hemoperfusion and hemodynamics in patients with septic shock requiring high-dose norepinephrine: a predetermined analysis of a prospective cohort study

    Cohort studySepsis & infection

40. Crit Care8 May 2025

    Left ventricular unloading during extracorporeal cardiopulmonary resuscitation: a target trial emulation of the ELSO registry

    Cohort studyCardiac arrest

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